Meanwhile, Mane has undergone an operation on the thumb injury he sustained on worldwide duty with Senegal.
Speaking to the media, Netherlands boss Ronald Koeman explained the full extent of Van Dijk's injury but stressed that the centre-back should be able to play on Saturday. He is a fantastic partner, we discuss a lot of matters ever single day and I am very happy to play next to him.
"Mane's recovery will be monitored over the next couple of days ahead of the Reds' return to action at Huddersfield Town on Saturday".
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Commenting on how the tables have turned in the last few years, Scholes said, "It shouldn't make any difference but it does". We will try to be clinical in the chances we have, defend well and play with confidence.
Liverpool boss Jurgen Klopp blasted the Uefa Nations League last week, saying the global windows now put too much strain on players so the German will be left ruing this weekend.
Liverpool chief executive Peter Moore insists the club are back where they belong and his task now is to ensure manager Jurgen Klopp gets the funds he needs to keep them there.
The Reds trio have all been suffering with various injuries, with Van Dijk and Salah picking up issues during worldwide match.
Van Dijk, 27, broke two of his ribs against former club Southampton on September 22nd but has carried on playing and joined up with the Netherlands for the worldwide break.