The Argentine superstar was rested along with nearly the entire XI that had played in Manchester, for the weekend LaLiga 0-0 draw over bottom side Huesca.
"For me, Luis is the same as always, which is playing at the high level he always maintains", Valverde said last month after Suarez earned a penalty and set up another goal in a 5-1 win over Lyon in the round of 16.
Dembele came closest to a goal in the first half after a brilliant reverse pass from the talented Riqui Puig, one of a number of youngsters given a chance to impress.
With a cut on the bridge of his nose and his eyelid, the 31-year-old was taken off the pitch as play resumed at Old Trafford.
'We will be true to our style but we are also aware of what they have in attack and the game can't become you attack us, we attack you. "The first leg result is not definitive". He also handed defender Paolo Gozzi, 17, his Serie A debut.
"We will make changes but with the aim of putting out a competitive team".
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The club is now at sixth in the Premier League table and faces an uphill task to secure Champions League qualification places. Sometimes you can't always be on your game and we have to be honest that today and in the Watford game we have been poor.
"We paid a little for our inexperience", said Allegri.
And this away match will be the toughest game of the likeable Norwegian's at the club yet.
It was SPAL's first win against the Italian champions since February 1957 and only Juventus' second league defeat of the season.
Overall, they were better than Huesca but never really got out of second gear. He rediscovered some enthusiasm today and it wasn't easy for him psychologically of late to have only 20 minutes or so and then get hurt again.
Kean opened after half an hour with Joao Cancelo pushing through the right with his shot going wide before the teenager stuck out his foot to redirect the ball home.
But SPAL held on to move up to 13th, seven points above the drop zone, having already beaten Champions League-chasing Lazio and Roma.
A clever touch and finish from inside the box by from SPAL's No 10 Floccari gave his side the lead in the 72nd minute just as Juventus had started to increase the pressure.