Peart was seen as one of the industry's most technically proficient rock drummers.
In a statement released this afternoon, Peart's Rush bandmates - Geddy Lee and Alex Lifeson - called Peart their "friend, soul brother and bandmate over 45 years", and said he had been "incredibly brave" in his battle with cancer.
Peart was born on September 12, 1952, in Hamilton, Ontario, Canada, and after taking piano lessons as a child, he took up the drums at age 14.
Manchester United's Harry Maguire out with muscle tear in hip
The Carabao Cup semifinal between Manchester United and Manchester City will be played at the Old Trafford . They were caught on the counter-attack for the second, when Bernardo slipped a through ball to Mahrez.
Rush is a staple of classic rock radio with such enduring songs as "Tom Sawyer", "The Spirit of Radio", "Limelight", "Freewill", "Subdivisions", "Closer to the Heart" and "New World Man" - all fueled by Peart's drumming and lyrics. "As far as I was concerned, he was hired from the minute he started playing". Rush went on to produce 10 platinum albums in the United States from 1975 through 1981.
Peart had announced his retirement in 2015. They'd been married for more than 20 years.
He was also an acclaimed author with books including his debut The Masked Rider: Cycling in West Africa, and Ghost Rider: Travels on the Healing Road. "Neil was one of the great drummers and he'll be missed".
His survivors include his wife Carrie and daughter Olivia.