The "COPCOV" trial is an worldwide study led by the University of Oxford, with support of a tropical medicine unit in Bangkok.
The COPCOV trial is being run at the Brighton and Sussex University Hospitals and at the John Radcliffe Hospital in Oxford.
But its effectiveness for treating coronavirus has been a subject of debate: A recent analysis of the use of the drug to treat COVID-19 patients in US veterans' hospitals found no benefit to using the drug and that there were more deaths among those given hydroxychloroquine versus standard care.
An additional four sites are expected to open by end May, towards a total of 25 COPCOV sites in the United Kingdom, by the end of June.
Chloroquine, hydroxychloroquine or a placebo will be given to more than 40,000 healthcare workers from Europe, Africa, Asia and South America.
Results are expected by the end of 2020.
'We really do not know if chloroquine or hydroxychloroquine are beneficial or harmful against COVID-19.
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A trial to see whether two anti-malarial drugs could prevent Covid-19 has begun in Brighton and Oxford. That's what COPCOV is - and why we're doing this study, ' said Prof White.
The human guinea pigs taking part include frontline healthcare workers at high risk of exposure to the virus, as well as patients.
Dr Nespolon noted that attempts to have the drug prescribed and dispensed for COVID-19 would cause shortages for those who are normally prescribed it. A widely available, safe and effective vaccine may be a long way off.
It will be open to British participants who are in close contact with patients with proven or suspected COVID-19.
The 3,000 health care workers and first responders in southeast MI selected for the study each received unmarked vials with either a daily dose of hydroxychloroquine, a once-a-week dose, or a placebo. In Asia they will receive either chloroquine or a placebo. The selection will be random and neither researchers nor volunteers will know which one they're receiving. HCQ studied to avoid and treat coronavirus disease 2019 (COVID-19). Hydroxychloroquine and chloroquine have shown positive results in small-scale studies and anecdotally, but there are still many unknowns. If - and only if - they are effective, these drugs can be scaled up and rolled out quickly across the world, ' said Nick Cammack, COVID-19 Therapeutics Accelerator Lead at Wellcome.
The UK-based medicines manurfacturer Accord Healthcare has donated more than two million tablets to allow the trial to go ahead.
The president began touting the benefits he believes would ensue to fight the coronavirus from the widespread use of hydroxychloroquine, a drug used to treat malaria which we have since learned from doctors, including the esteemed Trump Coronavirus Task Force member Dr. Anthony Fauci, has no proven effects against the virus we now face, and which has brought about cardiac maladies and death in many.