Four security guards of PSX, who were deployed at the main gate of the building embraced martyrdom while resisting the attackers.
The Baloch Liberation Army (BLA) is one of half a dozen armed resistance groups in Balochistan and has launched previous attacks in Pakistan.
Pakistan has always been plagued by Islamist militant violence but attacks have become less frequent in recent years after military operations against various factions in strongholds along the Afghan border.
Police and Rangers have cordoned off the area and the injured are being shifted to nearby hospitals. The media also reported that security forces are in a gun fight with 4 armed men.
Policemen and security officials are among those confirmed dead, according to Mohammad Azeem, an official with the Edhi rescue centre, a prominent local charity service.
It is not clear if more assailants were involved and a search of the premises is continuing.
The Pakistan Stock Exchange did not suspend trading during the attack, Chief Executive Furrukh Khan said. The latest updates inform that all four terrorists have been killed by the police.
In Karachi, security forces have foiled a terrorist attack on Pakistan Stock Exchange killing all the terrorists.
Four militants have stormed the PSX building and opened indiscriminate fire, the report said.
He said that the terrorists had planned a long assault, that included bloodshed and holding people inside the building hostage.
Sindh Chief Minister Murad Ali Shah condemned the incident, saying that the attack was "akin to an attack on national security and economy". Gen Omar Ahmed Bokhari - who oversees the paramilitary Rangers force which took part in the operation - accused neighboring India of aiding the attackers by allegedly activating "sleeper cells" that Pakistan claims Indian intelligence has planted throughout the country.
Two persons were killed in the attack.
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