The company earlier said it saw no evidence of a security breach or hack, but was investigating internal causes for the problems.
A brief message on Twitter's status site, posted at 10.56am NZT, says there is an "irregularity with Twitter APIs" (application programming interfaces) and that "We are now investigating this issue".
When trying to access Twitter's website, users were seeing "Something went wrong" errors, as well as other messages stating that Twitter is aware of the problem and is working on restoring access.
The service was later largely restored, and the California-based company said the site should soon be working for all of its users.
Biden: Voters "don't deserve to know" if he'd pack the Supreme Court
Biden told CNN WKRC affiliate in Cincinnati: "I am not a fan of shortcut packaging, but I don't want to get off all this stuff". Paying taxes, cleaning toilets, and cleaning up after our dogs are all things people are not thrilled to do.
The service was at least partially back up and running for some users by around 7 p.m. ET, when just 6,026 outages were reported on the monitoring site.
Complaints were registered as whenever the user tried to post a message, it showed, "Oops, something went wrong!" The social media platform noted, "Most of you should be back to Tweeting".
Twitter banned the article from being circulated on the site, without offering an explanation as to why.
Social media platforms like Twitter have become lifelines for many as a source of news and information-particularly during the ongoing COVID-19 pandemic.
Senate Republicans vowed Thursday to subpoena Dorsey to appear before the Judiciary Committee days before Election Day over Twitter blocking the story.
Sadly these outages do not appear to last for long when they do crop up.