It might be as simple as having a lunar rover drag icy rocks and soil into a sunlit spot and collect water as it evaporates.
The aim is to sustain that base by tapping into the Moon's natural resources.
The discovery raises the possibility that water could be distributed across the moon's surface, rather than in just in the cold shadow of craters, which are less accessible, NASA scientists said.
The data collected by the researchers suggest that one cubic meter of the lunar soil in the crater could contain roughly an equivalent of a 12-ounce (355 milliliter) bottle of water.
"It's far easier to travel when don't have to carry everything with you that you might need once you're there", Jacob Bleacher, chief exploration scientist for NASA's Human Exploration and Operations Mission Directorate, said during the teleconference.
Revealed with the help of the Stratospheric Observatory for Infrared Astronomy (SOFIA) flying observatory, this discovery shows that water may exist throughout the moon's surface, not just frozen in the coldest, darkest craters on the moon as was previously expected. Previous observations of the Moon's surface detected some form of hydrogen, but were unable to distinguish between water and its close chemical relative, hydroxyl (OH).
This "suggests that water could be much more widespread on the Moon than previously thought", Hayne told AFP.
Dr Sargeant explained that this meant developing "a more sustainable way of doing space exploration". NASA's Paul Hertz says the findings could have enormous implications.
To find out, Paul Hayne, a planetary scientist at the University of Colorado, Boulder, and his colleagues estimated the number and size of permanently shadowed polar regions, where temperatures remain below -163°C.
The first of these new discoveries was made from an airborne infrared telescope known as Sofia.
The Earth as seen from the Moon. It could be arriving aboard the micrometeorites that routinely rain down upon the lunar surface and are being protected from the harsh environment within pencil tip sized beads of glass formed during impact. In fact, Isro plans to launch the Chandrayaan-3 with a focus on the lander mission in coming 1 to 2 years to continue its water and mineral exploration mission on Moon.
"This could have some influence".
"The origin of water on the moon is one of the big-picture questions we are trying to answer through this and other research", Hayne said. "But this gives us more options and makes it an even more exciting place to go".
Experts will now try to figure out exactly how the water came to form and why it persists.
A handful of space agencies, including NASA and the European Space Agency, are examining ways to identify and extract water from the moon.
"Water on the surface of the moon can be used for several very important things, such as sustaining astronauts, creating oxygen and hydrogen for rocket fuel or power generation, or conducting horticulture experiments", says Craig Lindley, a computational modeling expert at Australia's science agency, CSIRO, developing technology to map the moon's water ice.
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